Headache
Headache is a painful sensation in any region of the head, ranging from sharp to dull, that may arise from primary neurological mechanisms or secondary to an underlying medical condition.
Murtagh Diagnostic Strategy
| Category | Diagnosis | Key Discriminator | Cantonese Question / Finding | Probability |
|---|---|---|---|---|
| Probability Diagnosis | Tension-type headache | Bilateral, band-like, no N/V, wax-and-wane, stress-related | 「頭痛係唔係兩邊、好似條帶咁箍住?」 | ~50% |
| Migraine | Unilateral pulsatile, 4–72h, N/V, photo/phonophobia, debilitating (POUND) [3][6] | 「痛嗰陣會唔會跳住痛、想嘔、怕光?」 | ~20% | |
| Serious Not To Miss | Brain tumour / ↑ICP | Progressive headache, worse morning/Valsalva, focal deficit, papilloedema [5] | 「頭痛係唔係一路惡化?朝早特別痛?」 | ~1% |
| Subarachnoid haemorrhage | Thunderclap "worst headache of my life" ± LOC, meningism [1][2] | 「有冇試過突然之間好似爆炸咁痛,一世人咁痛?」 | <1% | |
| Meningitis/encephalitis | Fever + headache + neck stiffness + confusion | 「有冇發燒、頸硬、意識模糊?」 | <1% | |
| GCA (temporal arteritis) | Age > 50, temporal tenderness, jaw claudication, ↑ESR [8] | 「食嘢嗰陣會唔會覺得顎骨好攰好痛?」 | <1% | |
| Pitfalls | Medication overuse headache | Analgesic ≥ 15 d/month; headache paradoxically worsens | 「你止痛藥一個月食幾多日?」 | ~10% |
| Cervical spondylosis (referred) | Occipital, a/w neck stiffness/pain, worse with neck movement | 「痛係唔係喺後尾枕,郁條頸痛啲?」 | ~5% | |
| Acute glaucoma | Eye pain + red eye + halos + decreased vision + hard globe [10] | 「眼有冇痛、紅、睇嘢有光圈?」 | <1% | |
| Masquerades | Depression | Low mood, anhedonia, insomnia, somatic headache | 「最近有冇心情低落、對嘢冇興趣?」 | ~10% |
| Drug-induced headache | Nitrates, CCB, cilostazol, OCP [4] | 「最近有冇食新藥?」 | ~5% | |
| Phaeochromocytoma | Classic triad: headache + sweating + tachycardia; paroxysmal HTN [11] | 「痛嗰陣有冇標汗、心跳得好快?」 | <1% | |
| Trying to Tell Me Something? | Psychosocial stress / anxiety | Work/family stress, exam pressure, health anxiety (fear of brain tumour) | 「最近有冇乜嘢事令你壓力好大?」 | ~20% |
| Time | Task | Cantonese Key Phrases | Why It Scores Marks |
|---|---|---|---|
| 0:00–0:30 | Friendly opening, rapport, set agenda | 「你好呀,我係X醫生。今日想傾下你嘅情況,大概會問下你嘅頭痛同埋其他相關問題,最後睇下可以點樣幫到你,好唔好?」 | Scores interpersonal marks: greeting, introduction, signposting, permission |
| 0:30–2:30 | HPI — SOCRATES of headache + red flags | 「頭痛幾時開始㗎?」「痛喺邊度?一邊定兩邊?」「點痛法?跳住痛定好似條帶咁箍住?」「有幾痛呀,十分入面你畀幾多分?」「有冇嘢令到佢痛啲或者好啲?」「痛嗰陣有冇覺得想嘔、怕光怕嘈?」「有冇試過好突然好嚴重嘅頭痛,好似爆炸咁?」(thunderclap) 「有冇發燒、頸硬、手腳冇力?」 | Captures chief complaint + red flags systematically; directly maps to Case Report Q1 |
| 2:30–3:30 | PMH, drug Hx, allergy, family Hx, social Hx | 「之前有冇乜嘢病底?」「而家食緊乜嘢藥?有冇食止痛藥?食咗幾耐?」「有冇藥物敏感?」「屋企人有冇偏頭痛或者其他嚴重病?」「你做咩工作?最近瞓得好唔好?有冇飲酒食煙?」 | Medication overuse headache is a common pitfall; social Hx screens psychosocial |
| 3:30–4:30 | ICE — uncover hidden agenda | 「你自己覺得頭痛係乜嘢原因呢?」(Ideas)「有冇特別擔心嘅嘢?例如驚係腦入面有嘢?」(Concerns)「你今日嚟最想我幫你做啲乜?」(Expectations)「點解揀今日嚟睇呢?」(hidden agenda — RFC) | ICE = core exam marks (Q3); "Why today?" reveals the real RFC |
| 4:30–5:15 | Focused systems review + functional impact | 「有冇影響到你返工或者湊小朋友?」「有冇心情唔好,訓唔著?」「有冇視嘢模糊、成日撞到嘢?」 | Biopsychosocial problems (Q5b); screens depression masquerade |
| 5:15–6:00 | Summarise, empathy, safety-net, close | 「等我總結下:你頭痛咗__,主要係__,最擔心__。我理解你嘅擔心。」「如果突然頭痛好嚴重、嘔、手腳冇力、或者講嘢唔清楚,要即刻去急症室。」「有冇嘢想補充?」 | Summarising + empathy + safety-net + checking understanding all score interpersonal marks |
Uncovering the hidden agenda: The presenting symptom is headache, but the RFC is often a specific fear (e.g. brain tumour, stroke) or a functional trigger (e.g. headache affecting work/exams, relationship stress). Always ask 「點解揀今日嚟睇呢?最近有冇咩事令你特別擔心?」
| Domain | English Question | Cantonese Question | Why It Matters | If Positive Think Of |
|---|---|---|---|---|
| Onset | When did it start? Sudden or gradual? | 「幾時開始痛?係突然之間痛定慢慢嚟?」 | Thunderclap onset → SAH [1][2] | SAH, dissection, CVST |
| Site | One side or both? Where exactly? | 「痛邊度?一邊定兩邊?眼周圍痛?」 | Unilateral → migraine/cluster; bilateral → TTH/↑ICP | Periorbital → cluster/glaucoma |
| Character | Throbbing, band-like, or stabbing? | 「點痛法?跳住痛、箍住痛、定刺痛?」 | Pulsatile + unilateral + N/V = migraine (POUND mnemonic) [3] | Migraine, TTH, neuralgia |
| Severity | How severe, 0–10? | 「十分入面幾痛?有冇影響到你做嘢?」 | Debilitating → migraine; "worst ever" → SAH | SAH if worst-ever headache |
| Duration | How long does each episode last? | 「每次痛幾耐?」 | 4–72h = migraine; 15min–3h = cluster; 30min–7d = TTH [3][4] | Classifies primary headache |
| Frequency | How often? How many days/month? | 「一個月痛幾多日?」 | > 15 days/month → chronic; medication overuse? | Chronic migraine, MOH |
| Aggravating | Worse with cough/bending/lying? | 「咳嗽、彎低身或者瞓低嗰陣會唔會痛啲?」 | Worse supine/Valsalva → ↑ICP [2][5] | SOL, hydrocephalus, IIH |
| Relieving | Better in dark room? With rest? | 「瞓喺暗房會唔會好啲?」 | Dark quiet room → migraine; restless → cluster | Primary headache type |
| Aura | Flashing lights or zigzag lines before? | 「痛之前有冇閃光、鋸齒形嘅嘢喺眼前?」 | Visual aura (scintillating scotoma) = classical migraine [6] | Migraine with aura |
| N/V, photo/phonophobia | Nausea, vomiting, light/noise sensitive? | 「有冇覺得想嘔?怕光怕嘈?」 | Key migraine features [3] | Migraine |
| Autonomic features | Eye tearing, nose blocked, eye red? | 「痛嗰邊有冇流眼水、鼻塞、眼紅?」 | Ipsilateral autonomic = cluster / TAC [4] | Cluster headache |
| Fever/neck stiffness | Any fever or stiff neck? | 「有冇發燒?條頸硬唔硬?」 | Meningism → meningitis/SAH [1][2] | CNS infection, SAH |
| Neuro symptoms | Weakness, numbness, speech problem? | 「手腳有冇冇力、痺、講嘢唔清楚?」 | Focal deficit → stroke/SOL [5] | Stroke, brain tumour |
| Vision | Blurred vision, visual field loss? | 「有冇視嘢模糊或者盲咗一邊?」 | Bitemporal hemianopia → pituitary tumour [7]; amaurosis fugax → GCA | Pituitary tumour, GCA, glaucoma |
| Jaw claudication/scalp tenderness (if > 50y) | Pain when chewing? Scalp tender? | 「食嘢咀嚼嗰陣會唔會痛?摸頭皮有冇痛?」 | Jaw claudication = GCA [8] | GCA — urgent |
| PMH | Any prior diagnoses? | 「之前有冇乜嘢病底?高血壓、糖尿病?」 | HTN → hypertensive crisis; cancer → mets | Secondary causes |
| Drug Hx | What medications? Painkillers how often? | 「而家食緊乜嘢藥?止痛藥一星期食幾多日?」 | Analgesic > 15 days/month → medication overuse headache (MOH) [4] | MOH — common pitfall |
| Allergy | Drug allergies? | 「有冇藥物敏感?」 | Safety | — |
| Family Hx | Family history of migraine? | 「屋企人有冇偏頭痛?」 | 70% migraineurs have +ve FHx [3] | Migraine |
| Social Hx | Work, stress, sleep, alcohol, smoking | 「做咩工作?最近壓力大唔大?瞓得好唔好?有冇飲酒?」 | Stress/sleep → TTH; alcohol trigger → cluster [4] | TTH, cluster, depression |
| Mood | Feeling down? Anxious? | 「最近心情點?有冇唔開心、好大壓力?」 | Depression masquerade [9] | Depression, anxiety |
| Functional impact | Affecting work/daily life? | 「有冇影響到你返工、做家務?」 | Q5b social problem | Disability |
| Menstrual (if female) | Relation to period? OCP use? | 「頭痛同月經有冇關係?有冇食避孕藥?」 | Menstrual migraine; OCP + migraine with aura → stroke risk [3] | Migraine, contraindication to OCP |
Case Report Form Answer Builder
- CC: Headache for [duration]
- HPI high-yield points to capture:
- SOCRATES: site (uni/bilateral), onset (sudden vs gradual), character (pulsatile/band-like/stabbing), radiation, associated symptoms (N/V, photophobia, phonophobia, aura, autonomic features), timing (duration of each attack, frequency, diurnal pattern), exacerbating/relieving factors, severity
- Red flags screened: SNOOP (systemic symptoms, neurological signs, onset sudden, other features, progression) [12]
- Temporal profile: acute/subacute/chronic; episodic vs daily
- Medication use: type, frequency, response
- Examples:
- "Patient presented because headache has become more frequent and is worried it could be a brain tumour"
- "Patient came today because headache is affecting work performance"
- "Patient's family member recently had a stroke, prompting concern"
- How to phrase: One sentence linking the symptom to the patient's reason for attending today. Always ask 「點解揀今日嚟?」
| Component | Likely Examples | Exact Wording for CRF |
|---|---|---|
| Ideas | "I think it might be stress" / "I worry it's a brain tumour" | "Patient thinks the headache is caused by work stress" |
| Concerns | Fear of brain tumour, stroke, aneurysm; fear of medication side effects | "Patient is worried that the headache could be due to a brain tumour" |
| Expectations | Wants a brain scan / wants reassurance / wants stronger painkillers / wants a referral | "Patient expects to have a CT brain scan to rule out serious causes" |
- In most FM station setups: Tension-type headache (most common) or Migraine (if unilateral, pulsatile, N/V, photophobia)
- Minimum supporting evidence for TTH: bilateral, band-like, no N/V, stress-related, no red flags
- Minimum supporting evidence for migraine: ≥2 of POUND criteria [3]
| DDx | Key Discriminator |
|---|---|
| Migraine (if TTH is main dx) or TTH (if migraine is main dx) | Character + associated symptoms |
| Medication overuse headache | Analgesic ≥ 15 d/month, paradoxical worsening |
| Cervical spondylosis (referred headache) | Occipital location, neck stiffness, worse with movement |
(If red flags present, swap in SAH, brain tumour, meningitis, or GCA as appropriate)
| Domain | Example |
|---|---|
| Biological | Recurrent headache with inadequate pain control / medication overuse |
| Psychological | Anxiety about brain tumour / underlying depression / stress |
| Social | Reduced work productivity / inability to care for children / social withdrawal |
| Diagnosis / DDx | Best Supporting Physical Sign | How to Elicit It | Why It Supports This Diagnosis |
|---|---|---|---|
| Tension-type headache | Pericranial muscle tenderness on palpation | Palpate temporalis, frontalis, masseter, trapezius with firm rotary pressure | Tenderness of pericranial muscles is the hallmark physical finding in TTH |
| Migraine | No reliable physical sign during interval; during attack — photophobia elicited by penlight | Ask patient to look at bright light | Migraine is a clinical diagnosis; exam is typically normal between attacks. If during attack: allodynia, photophobia |
| SAH | Neck stiffness (meningism) [1][2] | Passive neck flexion — resistance/pain; Kernig's/Brudzinski's sign | Blood in subarachnoid space irritates meninges |
| Meningitis | Neck stiffness + fever | Passive neck flexion; check temperature | Meningeal inflammation |
| Brain tumour / ↑ICP | Papilloedema on fundoscopy [5] | Direct ophthalmoscopy — blurred disc margins, loss of venous pulsation | Raised ICP causes optic disc swelling |
| GCA | Tender, thickened, non-pulsatile temporal artery [8] | Palpate superficial temporal artery — tenderness, beading, reduced/absent pulse | Inflamed temporal artery in GCA |
| Acute glaucoma | Hard globe on palpation + mid-dilated fixed pupil [10] | Gentle bidigital tonometry; examine pupil | Raised intraocular pressure |
| Cluster headache | Ipsilateral conjunctival injection, lacrimation, ptosis (partial Horner's) during attack [4] | Observe during attack — eye red, tearing, droopy lid | Trigeminal autonomic activation |
Must-Not-Miss Red Flags — SNOOP
SNOOP mnemonic for headache red flags [12]:
- Systemic symptoms (fever, weight loss, cancer, immunocompromised, pregnancy)
- Neurological symptoms (confusion, focal deficits, seizures, papilloedema, meningism)
- Onset sudden/new — thunderclap = SAH until proven otherwise → urgent NCCT brain → LP if CT negative [1][2]
- Other features (trauma, worse supine/Valsalva, visual symptoms, medication overuse)
- Progression or change in pattern of previous headache
Urgent referral if any SNOOP red flag is present.
Top traps that lose marks:
- Forgetting to ask about medication overuse — analgesic ≥ 15 d/month is one of the most common missed diagnoses in FM
- Not asking ICE — students lose Q3 marks entirely by not exploring ideas, concerns, and expectations
- Not asking "Why today?" — the RFC is often different from the headache itself (e.g. a colleague had a stroke)
- Jumping to red flags without characterising the headache first — SOCRATES comes before red flags
- Forgetting GCA in patients > 50 — always ask about jaw claudication and scalp tenderness [8]
- Writing "migraine" as diagnosis without supporting criteria — need ≥2 of POUND
- Not mentioning a psychological problem in Q5b — depression/anxiety is almost always relevant in chronic headache
- Missing menstrual migraine trigger in females — high-yield for FM
Safety-net closing line: 「如果你突然之間頭痛好嚴重、嘔、手腳冇力、講嘢唔清楚、或者發燒頸硬,要即刻去急症室。」
High Yield Summary
What to ASK: SOCRATES → red flags (SNOOP) → medication use → ICE → "Why today?" → mood → functional impact
What to WRITE:
- Q1: CC with duration + key SOCRATES points + red flags screened
- Q2: One sentence linking symptom to why the patient came today
- Q3: Patient's own idea, specific concern, and what they want done
- Q4: TTH or migraine (most likely in FM) with minimum criteria
- Q5a: Migraine/TTH (whichever isn't Q4) + MOH + cervical spondylosis (or SAH/GCA if red flags)
- Q5b: Bio (headache itself) + Psych (anxiety/depression) + Social (work/family impact)
- Q6: Pericranial tenderness (TTH) or papilloedema (↑ICP) or temporal artery tenderness (GCA)
What NOT to MISS: Thunderclap → SAH; age > 50 new headache → GCA; analgesic overuse → MOH; mood → depression masquerade
Active Recall - Family Medicine Clinical Test
[1] Lecture slides: GC 109. Headache and loss of consciousness Acute stroke, subarachnoid haemorrhage and vascular malformation.pdf (pp. 16, 1–2) [2] Lecture slides: GC 082. Severe headache_headache and neuralgia; neuro-imaging I.pdf (p. 45) [3] Senior notes: Adrian Lui Pediatrics Notes.pdf (pp. 109, 111) [4] Senior notes: Maksim Medicine Notes.pdf (p. 255) [5] Senior notes: Ryan Ho Neurology.pdf (p. 57) [6] Past papers: 2021 Fourth Summative Assessment MCQ.pdf (Q40, p. 15) [7] Senior notes: Block A - I keep on bumping into people on my side_ pituitary tumours; hypopituitarism.pdf (p. 1) [8] Senior notes: Block A - Rheumatology Interactive Tutorial.pdf (p. 1) — GCA/PMR case [9] Senior notes: Ryan Ho Fundamentals.pdf (pp. 312–313) [10] AOS material: AOS - Ophthalmology.pdf (p. 6) — acute glaucoma scenario [11] Senior notes: Block A - I have fluctuating BP_ cushing syndrome; adrenal diseases and tumours; other endocrine tumours.pdf (p. 24) [12] Senior notes: MBBS Final MB (Medicine) (Felix PY Lai).pdf (p. 1143) — SNOOP mnemonic
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