CFB OT04 Reconstruction

CFB OT04 Reconstruction refers to a surgical procedure involving the rebuilding or repair of the common femoral bifurcation (the junction where the common femoral artery divides into the superficial and deep femoral arteries), typically performed to restore blood flow in patients with peripheral arterial occlusive disease.

Reconstruction — Exam-Ready Comprehensive Notes

Lecture Map

Reconstruction is the rebuilding of tissue, anatomy, and function after congenital difference, disease, trauma, or surgical resection. This lecture (CFB OT04, Dr. WY Ip) uses orthopaedic and hand-surgery cases to teach the 5 Rs: Remove, Repair, Replace, Regenerate, and Rehabilitate. They are a planning checklist, not a mandatory sequence: a case may need only some of the five, and rehabilitation begins during planning rather than after surgery. [1]

To understand the whole range of conditions & tissues requiring reconstruction; to appreciate multiple methods of reconstruction; to understand such with examples; to be motivated by the challenges with reconstruction. [1]

Reconstruction is the rebuilding of something after it has been destroyed. The activity of constructing something again involving 5 "R": Remove, Repair, Replace, Regenerate, Rehabilitate. [1]

Why the 5 Rs Matter

Think of reconstruction as a set of questions for every case:

RMeaningFirst-Principle RationaleExample
RemoveExcise pathological tissue (tumour, infection, necrosis, duplicated/fibrous tissue)You cannot rebuild on a diseased foundation; source control is paramountDebridement in necrotising fasciitis, excision of extra digit
RepairFix what is damaged but salvageable (fracture fixation, ligament tightening, wound closure)Restoring structural continuity preserves biomechanical functionFracture ORIF, tendon repair, skin closure
ReplaceSubstitute irretrievably lost tissue with graft, flap, prosthesis, or biomaterialLost tissue cannot regenerate quickly enough → need immediate structural/functional substituteSkin graft for burn, joint arthroplasty, free flap
RegenerateSupport biological repair or use tissue-engineered productsMay reduce the amount of donor tissue needed, but does not abolish donor-site morbidity in current routine practiceDermal templates; selected cell-based products; the lecture's historical stem-cell/PRP examples
RehabilitateRestore function through physiotherapy, splintage, orthoses, trainingReconstruction without rehabilitation = suboptimal functional outcomeHand therapy after tendon transfer, foot orthosis post-polydactyly

High Yield — 5 Rs

Every case in this lecture is framed through the 5 Rs. For exams, state which Rs apply and why; do not force all five into every answer.


Prevent potential harm; Relieve pain; Improve function; Improve cosmesis; Restore esteem; Better quality of life. [1]

Why each matters clinically:

ObjectiveClinical Rationale
Prevent potential harmE.g., removing a malignant tumour before it metastasises; correcting a deformity before secondary joint damage
Relieve painPain is often the primary indication driving patients to seek surgery (e.g., OA)
Improve functionThe most important surgical outcome — a beautiful reconstruction that doesn't work is a failure
Improve cosmesisEspecially important in head/neck, hand, and breast reconstruction; affects psychosocial wellbeing
Restore esteemDisfigurement profoundly impacts self-image and social functioning
Better quality of lifeThe ultimate measure of reconstructive success

Exam MCQ Trap

"Prevent aging" is NOT an objective of reconstruction. This is tested directly in the lecture's built-in MCQ #1. Reconstruction addresses pathology, not normal physiological aging. [1]


Absence; Extra (lump); Mal-alignment; Contracture. [1]

These four categories cover virtually every deformity you will encounter:

  • Absence — Congenital (e.g., absent radius) or acquired (e.g., post-amputation, post-tumour resection)
  • Extra — Congenital duplication (polydactyly) or neoplasms (lumps)
  • Mal-alignment — Fracture malunion, angular deformity, rotational mismatch
  • Contracture — Scarring, Dupuytren's, joint contracture from disuse or inflammation

Congenital and developmental abnormalities; Infections; Rheumatic disorders; Metabolic dysfunction; Degenerative disorders; Tumors and lesions that mimic them; Sensory disturbance and muscle weakness; Injury and mechanical derangement. [1]

This is the lecture's organising list for reconstructive examples, not a complete orthopaedic differential diagnosis.


Skin; Scar; Blood vessel; Nerve; Muscle/Tendon; Bone; Joint/Cartilage; Ligament; Composite; Biomaterials (e.g., metal, organic or inorganic). [1]

Why "composite" matters: Many reconstructions involve multiple tissue types simultaneously (e.g., an osteomyocutaneous free flap contains bone + muscle + skin + blood vessels). Real-world defects are rarely single-tissue.


Cosmetics; Prosthesis; Orthosis; Physiotherapy; Splintage; Medication (e.g., Botox). [1]

TechniqueDefinition & Key DistinctionExample
ProsthesisAn artificial device that replaces a missing body partArtificial limb, breast implant
OrthosisAn external device that supports/corrects a body part (does NOT replace it)AFO (ankle-foot orthosis), wrist splint
PhysiotherapyPassive/active mobilisation to correct deformity, strengthen muscles, restore ROMPassive mobilisation for mild deformity [1]
SplintageImmobilisation to reduce pain, protect repaired tissue, or prevent deformitySplint for OA digits, post-op hand splint [1]
BotoxChemodenervation — temporarily paralyses overactive musclesSpasticity management, cosmetic wrinkle reduction

Reading the Non-Operative Images

  • Prosthesis (slide 9): the artificial hand and running blades replace missing parts and can be optimised for different tasks; a prosthesis may restore useful function without recreating normal anatomy.
  • Orthosis (slide 10): the custom shoe insert accommodates/corrects the existing foot; it supports a body part rather than replacing one.
  • Passive mobilisation (slide 11): gentle serial correction can improve a supple congenital deformity, but a rigid deformity should not be forced.
  • Finger splints (slide 12): small ring-style splints can stabilise painful osteoarthritic joints while preserving pinch and writing. Immobilisation is therefore selective, not synonymous with resting the whole hand.

Exam MCQ Trap — Lecture MCQ #2

"Oral medication for pain relief" is NOT a usual reconstruction means. Pain relief is supportive, not reconstructive. The other choices (operation for tendon, prosthesis, physiotherapy, splintage) are all legitimate reconstruction modalities. [1]


Bone: Osteotomy, bone lengthening, graft. Joint/cartilage: transplant of small area, in vitro regeneration, osteotomy, arthrodesis, arthroplasty. Skin: skin graft, skin expansion, skin flap (flap = transplantation with blood supply). Muscle & tendon: tendon transfer, release, tenodesis. Nerve: graft, neurotization. Ligament: replaced with tendon, artificial materials. [1]

Key Definitions and First-Principle Explanations

TissueTechniqueWhat It IsWhy It Works
BoneOsteotomyCutting bone to realign itCorrects angular/rotational deformity; redistributes load across joint
Bone lengtheningGradual distraction osteogenesis (Ilizarov principle)New bone forms in the gap created by slow, controlled distraction (~1 mm/day)
Bone graftTransplanting autograft or allograft; synthetic substitutes are not literally graftsAutograft can provide osteogenic cells, signals, and scaffold; processed allograft is mainly osteoconductive and avoids a harvest site but has different incorporation and risk profiles [13]
JointArthrodesisSurgical fusion of a jointEliminates painful motion in a destroyed joint; sacrifices movement for stability and pain relief
ArthroplastyJoint replacement with prosthetic implantRestores motion in a destroyed joint; preferred when motion preservation is critical
Cartilage transplantAutologous chondrocyte implantation or osteochondral graftRegenerates hyaline-like cartilage over small focal defects
SkinSkin graftTransplanted skin WITHOUT its own blood supply; depends on recipient bed vascularitySplit-thickness (epidermis + partial dermis) or full-thickness (entire dermis); requires healthy, vascularised wound bed [3]
Skin expansionBalloon placed under skin, gradually inflated over weeksGenerates extra local skin with matching colour/texture for reconstruction
Skin flapTransplanted tissue WITH its own blood supply (pedicled or free)Survives independently of wound bed; used when bed is avascular or critical structures exposed [3]
Muscle/TendonTendon transferRerouting a functioning tendon to replace a non-functioning oneBorrows function from a redundant motor to restore lost movement
TenodesisFixing a tendon to bone to provide passive stabilisationCreates a passive check-rein effect (e.g., wrist tenodesis for tendon imbalance)
NerveNerve graftInterposition graft (usually sural nerve) to bridge a nerve gapProvides a conduit for axonal regrowth
NeurotizationTransferring a functioning nerve to a denervated muscleBypasses the injured nerve entirely; donor nerve reinnervates the target
LigamentTendon graftUsing autologous tendon (e.g., hamstring, palmaris longus) to reconstruct ligamentTendons can function as ligament substitutes after biological remodelling ("ligamentisation")
Artificial materialsSelected synthetic augmentation or replacementCan provide immediate mechanical support but has implant-specific indications and failure modes

The lecture's operative techniques align with the classic reconstructive ladder described in GC 192 and senior notes [2][3]:

Principle: Start at the simplest method that will achieve the reconstructive goal. Escalate only when simpler methods are inadequate. However, modern practice also uses a "reconstructive elevator" — jumping directly to the optimal method (e.g., free flap) when clinical context demands it.

From GC 192: the pathology determines what must be resected; reconstruction comes second. [2]

Key Principle

Never compromise oncological resection to make reconstruction easier. Resect adequately first, then reconstruct. [2]

Margin Safety Note

The fixed BCC/SCC/sarcoma centimetre figures in the older companion deck are not safe universal rules. Margin planning is tumour-, site-, and guideline-specific. A suspected soft-tissue sarcoma should be imaged and core-biopsied through a tract planned by a specialist sarcoma team; the operative aim is an en-bloc resection with negative margins, not an arbitrary cuff measured independently of anatomy. [9]


Clinical Case-Based Application of the 5 Rs

The lecture walks through eight diagnostic categories with specific examples. Below is a consolidated table:

Remove: extra digit. Repair: various tissue layers after trimming. Rehabilitate: foot orthosis or hand splint to protect repaired tissue during early stage. [1]

TissueOperative Technique
BoneExcise duplicated bone, realign digital bones
SkinExcise redundant skin, close
Muscle/TendonCombine tendons of 2 digits into one
LigamentTighten lax ligaments

What the photographs add (slides 14–18): the deck shows a postaxial extra toe and a duplicated thumb, followed by operative and early postoperative images. This is not simply "cut off the smaller digit." The surgeon assesses which digit has the better skeleton, nail, neurovascular supply, tendons, and joint stability; excises the less useful component; then reconstructs alignment, collateral ligament, tendon balance, nail fold, and skin. A temporary K-wire or splint may protect the reconstruction. Complex duplications therefore require radiographs and a tissue-by-tissue plan.

Remove: fibrous tissue connection between digits. Replace: skin deficit with skin graft. Rehabilitate: hand function training. [1]

TissueOperative Technique
BoneTrim to good shape
SkinCut at webs, skin graft
Muscle/TendonThe slide says "nothing can be done"; interpret this as anatomy-limited correction in this illustrated case, not a rule for every syndactyly

Multiple-stage operations to further improve function; cosmesis not the key concern. [1]

What the operative markings add (slides 19–23): interdigitating zig-zag flaps recreate the web and avoid a straight longitudinal scar that could contract. Separation creates a skin deficit, so a graft or local substitute may be needed. When several adjacent digits are joined, surgeons usually release one side of a digit at a time to protect its blood supply; this is the key reason for staged surgery. Later revision may be needed for scar contracture or web creep as the child grows. The priority is useful grasp and independent digit motion, not a perfectly normal appearance. [11]

Remove: infected & necrotic tissues. Repair: cut tissue repaired. Replace: skin deficit with skin graft, lost muscle with tendon transfer if can be done. Rehabilitate: maximise remaining muscle function with training. [1]

What the photographs add (slides 24–25): viable-looking skin can overlie extensive fascial and muscle necrosis. Management is immediate resuscitation, broad-spectrum IV antibiotics, and urgent exploration with radical debridement; repeat debridement is often required. Negative-pressure wound therapy (NPWT) may temporise a clean defect, but it does not replace source control. Graft/flap coverage and tendon transfer come only after infection and tissue viability are controlled.

Remove: inflamed tissue. Repair: lax ligament. Replace: damaged joint by fusion or arthroplasty. Rehabilitate: protect reconstructed tissue initially with splintage, training after tissue healing. [1]

TissueOperative Technique
BoneNo need to operate (unless erosion)
JointArthrodesis of lax, damaged joint
Muscle/TendonTendon transfer for ruptured tendons
LigamentTightening if joint salvageable

Why tendon transfer in RA? Chronic synovitis erodes tendons (especially extensor tendons over the dorsal wrist). The ruptured tendon cannot be repaired directly because the ends are frayed and attenuated. A working tendon is transferred to restore the lost function.

Current framing: the image shows established rheumatoid hand deformity with imbalance and loss of active function. Disease-modifying control of inflammation is foundational; synovectomy, tendon transfer, ligament balancing, arthrodesis, or arthroplasty are selected for pain, instability, rupture, and functional goals. "Bone: no need to operate" is only the lecturer's simplified tissue inventory for this case, not a general rule.

Remove: tophaceous material. Repair: lax ligament. Rehabilitate: protect reconstructed tissue initially with splintage. [1]

TissueTechnique
JointArthrodesis if joint damaged
SkinSkin flap if skin loss
LigamentReplaced with tendon if damaged by tophus

Do not mistake the photograph for first-line treatment: slides 29–32 show bulky hand/foot tophi being excised. Current care for tophaceous gout is treat-to-target urate-lowering therapy; ACR strongly recommends urate-lowering therapy when subcutaneous tophi are present. Excision is reserved for selected problems such as ulceration/infection, nerve or tendon compression, mechanical block, severe deformity, threatened skin, or diagnostic uncertainty. Surgery does not correct the underlying urate burden. [7]

Reading slides 33 and 35: the clinical photographs show hip/knee axis deformity, while the radiographs show non-uniform joint-space loss with osteophyte formation, subchondral sclerosis, and deformity. The operative montage contrasts load-redistributing osteotomy, motion-preserving arthroplasty, and motion-sacrificing fusion. Radiographic severity alone is not an indication for surgery; symptoms, function, goals, and response to non-operative care matter.

The conservative-treatment pictogram (slide 34) represents walking aids, activity/environment modification, footwear, raised seating, local heat, and analgesia. The aspirin bottle is a historical illustration rather than a current instruction. Core current management is information and self-management support, therapeutic exercise, and weight management when appropriate; medicines and aids are adjuncts. [8]

Operative options: [1]

  • Osteotomy — Realigns the limb to shift load from the diseased compartment to the healthy one. Best for young patients with unicompartmental disease.
  • Total joint replacement (arthroplasty) — Consider when pain, stiffness, and functional loss substantially affect quality of life despite appropriate non-operative care; the decision is shared and patient-specific. [8]
  • Arthrodesis (fusion) — Eliminates painful motion to gain stability. It is commoner as salvage in selected small joints/ankle than for hip or knee OA; the fused knee and hip images are historical/salvage examples, not routine modern first choices.
TissueTechnique
BoneOsteotomy
JointArthrodesis, arthroplasty
LigamentReconstruct if joint salvageable and there is imbalance

Remove: tumour with a cuff of normal tissue. Repair: cut tissue. Replace: lost tissue with composite tissue. Rehabilitate: protect reconstructed tissue initially with splintage, training after tissue healing. [1]

TissueTechnique
SkinSkin flap to cover large defect
Muscle/TendonLatissimus dorsi muscle transfer to replace lost muscles (finger & wrist extensors)
NervePreserved

Latissimus dorsi muscle with skin island for wound coverage & coverage of post-operative radiotherapy tubes & restore finger extension. [1]

What the sequence shows (slides 37–41): the forearm tumour and planned resection create a composite defect. A free functional latissimus dorsi muscle transfer brings artery, vein, motor nerve, muscle/tendon, and a skin paddle. The skin paddle closes the wound and covers the illustrated radiotherapy catheters; the reinnervated muscle is tensioned to power wrist/finger extension. The final image demonstrates both contour and active limb function, while the donor site leaves a long back/axillary scar.

Why latissimus dorsi? It is a broad, relatively expendable muscle with a reliable thoracodorsal pedicle and motor nerve. However, the lecture's "cuff of normal tissue" is conceptual: suspected sarcoma requires specialist MDT planning, a planned core-biopsy tract, and en-bloc resection to a negative margin determined by tumour biology and anatomical barriers. [9]

Remove: fibrous band & fascial layers. Repair: skin. Regenerate: axon distal to compression at 1 mm per day. Rehabilitate: mobilisation exercise and splintage to prevent deformity while waiting nerve regeneration. [1]

What the images show (slides 42–44): severe cubital tunnel syndrome can produce first-dorsal-interosseous wasting and an ulnar claw; the second image shows endoscopic-assisted decompression at the medial elbow. The target is complete release of compressive fascia while protecting the ulnar nerve, followed by splintage/therapy when indicated.

Key fact, with a caveat: regenerating peripheral axons are often estimated at about 1 mm/day, but this is an approximation after axonal injury, not a stopwatch for recovery after simple decompression. Recovery also depends on injury grade, duration, age, distance to the target, remyelination, and whether motor end plates remain viable. Final improvement after cubital tunnel release may take 12–18 months; severe longstanding wasting may not reverse even when decompression prevents further deterioration. [10]

Endoscopic-assisted release is a minimally invasive option. [1]

Remove: necrotic tissue. Repair: fix fracture. Replace: lost tissue with composite tissue. Rehabilitate: protect reconstructed tissue initially with splintage, training after tissue healing. [1]

TissueTechnique
BoneFixation, bone graft
JointArthrodesis of PIPJ (PIP joint)
SkinSkin flap from adjacent finger

Use tissue in neighbouring digit for coverage. Fix the bone. Preserve the severely damaged digit. [1]

Reading the image sequence (slides 45–50): the radiograph shows a severe open fracture, followed by external fixation. After debridement and bony stabilisation/grafting, a cross-finger flap from the neighbouring digit supplies vascularised skin to exposed structures. The two fingers are temporarily joined; at a later operation the pedicle is divided and the donor defect is skin-grafted. The trade-off is donor-finger morbidity and stiffness, so early supervised hand therapy after safe healing is integral to salvage.

Why arthrodesis of PIPJ? If the articular surface is irretrievably destroyed, fusion can provide a painless stable post for grip. The fusion angle is chosen by digit and task; there is no single 30–40° position for every PIP joint.


Future: no need for donor site. Stem cells present in adult can be stimulated to differentiate into various cell lines under proper stimulation in proper environment e.g., appropriate growth factors. Concept of tissue engineering: in vivo or in vitro production of certain tissue for replacement of lost tissue & function. [1]

The deck presents these as future-facing examples:

  1. Autogenous stem cells to promote ulcer healing [1]
  2. Platelet-rich plasma (PRP) to stimulate wound healing [1]
  3. Scaffolds for new skin regeneration [1]

What the images show (slides 52–54): marrow/blood is aspirated and centrifuged before material is injected into an ulcer; PRP is applied to a large wound; and a dermal scaffold is used under an occlusive/negative-pressure dressing before later skin coverage. A dermal template provides a matrix for vascular ingrowth and usually still needs definitive epithelial cover (often a split-thickness graft); it does not grow a complete normal skin organ by itself.

Current Evidence Guardrail

Do not present autologous stem-cell injection or PRP as routine substitutes for wound fundamentals. First correct perfusion, pressure/shear, infection, necrosis, glycaemic/nutritional factors, and provide appropriate debridement and coverage. Cell-based products and PRP are indication- and product-specific; many marketed regenerative products remain unapproved or insufficiently proven, and some have caused serious harm. [12]

Tissue engineering triad (not explicitly in slides but useful context):

  • Cells (stem cells or differentiated cells)
  • Scaffold (biological or synthetic matrix providing 3D structure)
  • Signals (growth factors, mechanical stimuli)

The slide asks which reconstruction "usually does not involve": excision; tissue from another body part; skin from a donor; bone from a donor; or donor-free biomaterial. The deck does not display an answer, so the earlier note's confident choice of D was unsupported.

How to Handle This MCQ

Do not learn this as a timeless clinical fact. In current practice, donor bone allograft is a recognised orthopaedic reconstructive material [13], whereas deceased-donor skin is generally temporary biological cover rather than definitive autologous skin replacement. That makes C the best modern reading if "donor" means another person, but the question is semantically ambiguous because surgeons also call the patient's harvest area a "donor site." Use a lecturer-provided answer key if this exact historical item reappears.


No cook book approach. Demands creativity. Requires dedicated team for good function & cosmesis. Improves quality of life of patient. High satisfaction for the team & patient. [1]

This is a philosophical point but examiners love to hear that reconstruction is individualised and multidisciplinary — the surgeon, physiotherapist, occupational therapist, prosthetist/orthotist, and the patient all contribute to the outcome.


Integration with Other GC Lectures

  • Surgical approaches: Open surgery, minimally invasive surgery (minimise scar), other destructive devices (cauterisation, cryosurgery, topical agents, laser ablation, radiofrequency, focused ultrasound)
  • Resection margins for cancer: the older deck supplied fixed example figures; use current tumour-specific guidance rather than carrying those figures across cancers [9]
  • Principle: Pathology dictates resection; reconstruction follows

  • Free cutaneous flaps after intraoral tumour resection → improve tongue mobility → better function
  • Free osteocutaneous flaps for mandibular reconstruction → restore swallowing and speech
  • Myocutaneous flaps or free jejunal grafts for pharyngeal reconstruction after laryngopharyngectomy
  • Stomach pull-up for oesophageal reconstruction after total laryngopharyngo-oesophagectomy

  • Prosthesis (implant) — Silicone or saline, placed submuscular or subglandular
  • Autologous — TRAM flap, DIEP flap, latissimus dorsi flap
  • Combination — Implant + autologous tissue

The formal reconstructive ladder from senior notes:

  1. Healing by secondary intention
  2. Primary closure
  3. Skin grafting (requires vascularised, uninfected bed)
  4. Local tissue transfer (flaps)
  5. Distant tissue transfer (pedicled flaps)
  6. Free tissue transfer (microsurgical)

ClassificationTypes
By compositionFasciocutaneous, myocutaneous, osteomyocutaneous
By contiguityLocal, regional, distant
By blood supplyRandom, axial, perforator
By transferPedicled, free (microsurgical)

ThemeHow It AppearsKey Discriminators
Objectives of reconstructionMCQ: "Which is NOT an objective?""Prevent aging" is the distractor; all others are valid objectives [1]
5 RsSAQ: "Describe reconstructive plan for [condition]"Must mention all applicable Rs; Rehabilitate is often forgotten
Graft vs flapMCQ/SAQ: "What is the difference?"Blood supply is the key distinction
Reconstructive ladderSAQ: "List methods in order of complexity"Secondary intention → primary closure → graft → local flap → distant flap → free flap [3]
Axonal regeneration rateSAQ/viva factoid1 mm/day — memorise this number [1]
Oncological reconstructionSAQ/viva: "What determines the resection?"Pathology and a specialist oncological plan determine resection; reconstruction must not compromise negative margins [9]
Arthrodesis vs arthroplastyMCQ: "Which is preferred for [scenario]?"Arthrodesis = pain relief but sacrifices motion; Arthroplasty = preserves motion but has implant-related complications

High Yield Summary

  1. Reconstruction = 5 Rs

    • Remove → Repair → Replace → Regenerate → Rehabilitate.
  2. Objectives

    • Prevent harm, relieve pain, improve function, improve cosmesis, restore esteem, better QoL. NOT "prevent aging."
  3. Non-operative

    • Prosthesis (replaces), Orthosis (supports), Physiotherapy, Splintage, Botox. NOT "oral medication for pain relief."
  4. Tissue-specific operative techniques

    • Bone (osteotomy, graft, lengthening), Joint (arthrodesis, arthroplasty), Skin (graft = no blood supply, flap = with blood supply), Nerve (graft, neurotisation; regeneration rate 1 mm/day), Tendon (transfer, tenodesis), Ligament (tendon graft, synthetic).
  5. Reconstructive ladder

    • Secondary intention → Primary closure → Skin graft → Local flap → Regional flap → Distant flap → Free flap. Choose the least complex option that reliably meets the functional and coverage goal; it is reasonable to "take the elevator" when a simpler rung is inadequate.
  6. Cancer reconstruction

    • Resection is dictated by pathology and specialist MDT planning; reconstruction comes second. Fixed centimetre margins are not transferable across tumour types.
  7. Regeneration

    • The deck's stem-cell and PRP cases are historical/emerging examples, not universal standard care. Dermal scaffolds support ingrowth but usually still require definitive coverage.
  8. Reconstruction is individualised, creative, and multidisciplinary.

    • No cookbook approach.

Active Recall - Reconstruction


[1] Lecture slides: CFB (OT04) Reconstruction.pdf (Dr. WY Ip) [2] Lecture slides: GC 192. I want to look better Plastic and reconstructive surgery.pdf (Resection & Reconstruction slide) [3] Senior notes: MBBS Final MB (Surgery) (Felix PY Lai).pdf (Plastic surgery diseases — Reconstruction in surgery, pp. 1172–1178) [4] Lecture slides: CFB 26_Lecture Note_ENT (I).pdf (Functional restoration and extensive resection sections) [5] Lecture slides: The Managment of breast cancer_Prof A Kwong 20_2_2020.pdf (Breast Reconstruction slide) [6] Senior notes: Maksim Surgery Notes.pdf (Wound healing and reconstruction, p. 343) [7] FitzGerald JD, et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care Res. 2020;72:744–760. https://doi.org/10.1002/acr.24180 [8] NICE. Osteoarthritis in over 16s: diagnosis and management (NG226). 2022. https://www.nice.org.uk/guidance/ng226/chapter/recommendations [9] Hayes AJ, et al. UK guidelines for the management of soft tissue sarcomas. Br J Cancer. 2024. https://doi.org/10.1038/s41416-024-02674-y [10] American Academy of Orthopaedic Surgeons. Cubital Tunnel Release. https://orthoinfo.aaos.org/treatment/cubital-tunnel-release [11] Pediatric Orthopaedic Society of North America. Hand Syndactyly. https://www.orthokids.org/conditions/hand-syndactyly/ [12] US Food and Drug Administration. Important Patient and Consumer Information About Regenerative Medicine Therapies. https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies [13] American Academy of Orthopaedic Surgeons. Bone and Tissue Transplantation. https://orthoinfo.aaos.org/en/treatment/bone-and-tissue-transplantation

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